Oxycodone how many

Based on these data, the following primary efficacy end points were determined: total pain relief 6 hours after dosing TOTPAR6 and sum of pain intensity differences 6 hours after dosing SPID6.

Other end points included the time to onset of pain relief, time to use of rescue medication, and patient's global rating of analgesic effectiveness. Tolerability was evaluated on the basis of observed and patient-reported adverse events and findings on physical examination. If you have a breathing problem such as asthma or COPD chronic obstructive pulmonary disease , talk with your doctor about whether this drug is safe for you.

Certain people should never take oxycodone: These include people who already have slow or shallow breathing, or who have too much carbon dioxide in their blood due to poor breathing. They also include people with acute or severe asthma. For all of these people, taking this drug could harm their breathing too much and cause death.

For people with gastrointestinal GI problems: Oxycodone can worsen certain stomach or bowel problems. This is because this drug makes it harder for food to move through your digestive tract. It can also make it harder for doctors to diagnose or find the cause of these problems. If you have a condition called a paralytic ileus, you should not take oxycodone.

Or if you have any type of GI obstruction, you should not take extended-release oxycodone. The immediate-release version may be used cautiously. For people with head injury: Oxycodone may cause increased pressure in your brain. It may also cause breathing problems. Both of these issues raise your risk of complications, and can cause death. For people with liver problems: Your body may process drugs more slowly. Your doctor may start you on a lower dosage.

For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well.

This may increase the levels of oxycodone in your body and cause more side effects. This medication may also decrease your kidney function, making your kidney disease worse. For people with seizure problems: Oxycodone may cause or worsen seizures.

If you have epilepsy , talk with your doctor about whether this drug is safe for you. Oxycodone may make your condition worse. Your doctor may prescribe a lower dosage of this drug.

For people with hypothyroidism low thyroid levels : Talk with your doctor about whether this drug is safe for you. Oxycodone could make your condition better or worse.

For people with urination problems: If you have trouble urinating due to certain problems, talk with your doctor about whether this drug is safe for you. These problems include an enlarged prostate, a bladder obstruction, or kidney problems.

Oxycodone can make it even harder for you to urinate, or make you unable to urinate. For people with pancreas and gallbladder problems: Oxycodone raises your risk of pancreatitis. If you have acute or chronic pancreatitis , this drug may worsen your condition. Talk with your doctor about whether this drug is safe for you. For pregnant women: Using oxycodone long term during pregnancy may cause withdrawal symptoms in your newborn child.

Symptoms include irritability, overactive behaviors, or an abnormal sleep pattern. They also include high-pitched crying, tremors, vomiting, diarrhea, or failure to gain weight. This drug should only be used in pregnancy if clearly needed. For women who are breastfeeding: Oxycodone is present in breast milk and may cause side effects in a child who is breastfed.

Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication. For seniors: The kidneys of older adults may not work as well as they used to. For people at risk of misuse, addiction, or overdose: Using oxycodone can lead to addiction and misuse, which can result in overdose or death. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.

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The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The health care team will closely monitor the person's breathing.

The person may receive:. Additional therapies may be needed if the person took hydrocodone and oxycodone with other drugs, such as Tylenol or aspirin. A large overdose can cause a person to stop breathing and die if not treated right away.

The person may need to be admitted to the hospital to continue treatment. Depending on the drug or drugs taken, multiple organs may be affected. This may affect the person's outcome and chances of survival. If you receive medical attention before serious problems with your breathing occur, you should have few long-term consequences. You will probably be back to normal in a day.

However, this overdose can be deadly or can result in permanent brain damage if treatment is delayed and a large amount of oxycodone and hydrocodone is taken.